 | 学位：博士 |
研究中心：食品微生物与生物技术研究中心 | |
研究领域：微生物活性代谢产物；益生菌发酵 | |
邮箱：zhangyanzqgh@163.com | |
办公电话： | |
通讯地址：新疆省石河子市北四路太阳集团tyc208 | |
个人简介
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张艳，博士，教授。主要从事益生菌发酵与功能食品开发工作，主持国家自然科学基金2项，校级课题2项，横向经费2项目，在国内外学术期刊上发表论文20余篇，其中SCI收录论文15篇，EI收录6篇；申请中国发明专利5项，其中授权发明专利2项；共同主编或参编著作2部。
社会兼职
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新疆微生物学会会员。
科研学术工作经历与教育背景
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2026.8——至今，太阳集团tyc，太阳集团tyc，教授
2019.4——2026.8，太阳集团tyc，太阳集团tyc，副教授
2016.6——2019.4，太阳集团tyc，太阳集团tyc，讲师
2013.9——2016.6，西北农林科技大学，食品科学，博士
2011.9——2013.6，西北农林科技大学，食品科学，硕士
2007.9——2011.6，西北农林科技大学，食品科学，学士
研究方向：
1.食品微生物代谢与调控；微生物源活性物质开发与利用；
2.益生菌转化活性物质及发酵产品开发；
3.新疆特色食品的功能活性研究。
科研项目
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1. 国家自然科学基金委员会，地区科学基金项目，31760446，新疆地区不同动物原奶微生物组及优势种群Lactococcus遗传结构的宿主特异性研究，2018.01-2021.12，37万元，主持。
2. 国家自然科学基金委员会，地区科学基金项目，32260568，Bifidobacterium animalis subsp.LactisHN-3代谢大果沙枣中植物源活性成分的转化机制研究，2022.01-2026.12，33万元，主持。
3.太阳集团tyc，新疆喀什地区双歧杆菌的寡糖代谢特异性及其与乳杆菌的代谢互补性研究，太阳集团tyc青年创新人才计划项目，CXBJ201901，2020.01-2022.12，15万元，主持。
4.太阳集团tyc，新疆少数民族群体母乳源双歧杆菌的分离筛选及益生特性研究，太阳集团tyc高层次人才启动项目，CZX201432R，2017.01-2020.12，5万元，主持。
5.横向课题，功能性酸奶粉系列产品的开发，2023.06-2024.06，30万元，主持。
6.横向课题，益生菌发酵饲料的开发，2023.06-2024.06，20万元，主持。
学术论文
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1. Wang, Yixuan, Li, Hui, Li, Xiaozhen, Wang, Chenxi, Li, Qianhong, Xu, Meng, Guan, Xiangluo, Lan, Zhenghui, Ni, Yongqing, & Zhang, Yan*. (2022). Widely targeted metabolomics analysis of enriched secondary metabolites and determination of their corresponding antioxidant activities in Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit juice enhanced by Bifidobacterium animalis subsp. Lactis HN-3 fermentation. Food Chemistry, 374.
2.Wang, Yixuan, Li, Wenhao, Wang, Xiaojun, Hu, Qi, Kong, Junkai, wang, Xiu, Lan, Zhenghui, Wang, Chenxi, &Zhang, Yan*. (2024). Investigation of volatile compounds during fermentation of Elaeagnus moorcroftii Wall.ex schlecht. juice by Bifidobacterium animalis subsp. lactis HN-3 and Lacticaseibacillus paracasei YL-29. Food Chemistry: X, 21.
3. Wang, Chenxi, Wang, Yixuan, Teng, Yingdi, & Zhang, Yan*. (2024). Win-win cooperation between plant substrates and probiotics: Revealing biotransformation and bioactive metabolites in Elaeagnus moorcroftii Wall. ex Schlecht fermented by Lacticaseibacillus paracasei YL-29. LWT, 204.
4. Wang, Yixuan, Wang, Chenxi, Shi, Junling, & Zhang, Yan*. (2024). Effects of derivatization and probiotic transformation on the antioxidative activity of fruit polyphenols. Food Chemistry: X, 23.
5. Wang, Chenxi, Wang, Yixuan, Teng, Yingdi, Kong, Junkai, Dong, Fujin, Du, Jie, & Zhang, Yan*. (2025). Cooperation mechanism of flavonoid transformation by Bifidobacterium animalis subsp. lactis and Lacticaseibacillus paracasei. International Journal of Food Microbiology, 429.
6. Zhenghui Lan, Xueling Zhang, Meng Xu, Junkai Kong, Xuancheng Zuo, Yixuan Wang, Chenxi Wang, Yingdi Teng, Yongqing Ni*, Yan Zhang*. Whole-genome resequencing and transcriptional profiling association analysis revealed the intraspecies difference response to oligosaccharides utilization in Bifidobacterium animalis subsp. lactis, Frontiers in Microbiology, 2024, 15: 1375384.
7. Yixuan Wang, Chenxi Wang, Zhenghui Lan, Yingdi Teng, Yongqing Ni*, Yan Zhang*. The Biotransformation and Influence on the Functional Activities of Metabolites during the Fermentation of Elaeagnus moorcroftii Wall.ex Schlecht. Juice by Bifidobacterium animalis subsp. lactis HN-3, Foods, 2024, 13(6): 926.
8. Baolong Luo, Fujin Dong, Yuyang Liu, Jie Du, Hailong Sun, Yongqing Ni, Yan Zhang*. Insights into the microbiota of raw milk from seven breeds animals distributing in Xinjiang China, Frontiers in Microbiology, 2024, 15:1382286.
9. Yingdi Tenga, Chenxi Wang, Wenhao Li, Yongqing Ni,Yan Zhang*. Growth promotion markers and functional metabolomic analysis of co-cultured Bifidobacterium animalis subsp. lactis HN-3 and Lacticaseibacillus paracasei YL-29 in Elaeagnus moorcroftii Wall.ex Schlecht juice. Food Science and Human Wellness, 2026.
10. Yan Zhang, Shi Junling*, Ni Yongqing, Liu Yanlin, Zhao Zhixia, Zhao Xixi, Gao Zhenhong.Tracing the mass flow from glucose and phenylalanine to pinoresinol and its glycosides in Phomopsis sp. XP-8 using stable isotope assisted TOF-MS, Scientific Reports, 2019, 9(1): 18495.
11. Xixi Zhao(1), Yan Zhang(1), Junling Shi*, Yanlin Liu , Yao Lu, ZiyangLian. Biosynthesis of antibacterial compound against multidrug resistant foodborne pathogens by Phomopsis sp. XP-8. Food Control, 2018, 95 (2019)223-231.
12. Qi Li(1),Yan Zhang(1), Jun-Ling Shi*,Yi-Lin Wang, Hao-Bin Zhao, Dong-yan Shao, Qing-Sheng Huang, HuiYang and Ming-Liang Jin.Mechanism and Anticancer Activity of the Metabolites of an Endophytic Fungi from Eucommia ulmoides Oliv. Anticancer Agents Med Chem, 2017, 17 (7) :982.
13. Yan Zhang, Junling Shi*, Zhenhong Gao, Jinxin Che, Dongyan Shao,Yanlin Liu. Comparison of pinoresinol diglucoside production by Phomopsis sp. XP-8 in different media and the characterization and product profiles of the cultivation in mung bean. Journal of the Science of Food and Agriculture, 2016, 96(12): 4015- 4025.
14. Yan Zhang, Junling Shi*, Zhenhong Gao, Riuming Yangwu, Huanshi Jiang, Jinxin Che, Yanlin Liu. Production of pinoresinol diglucoside, pinoresinol monoglucoside, and pinoresinol by Phomopsis sp. XP-8 using mung bean and its major components. Appl Microbiol Biotechnol, 2015, 99:4629–4643.
15. Yan Zhang, Junling Shi*, Laping Liu, Zhenhong Gao, Jinxin Che, Dongyan Shao, Yanlin Liu. Bioconversion of Pinoresinol Diglucoside and Pinoresinol from Substrates in the Phenylpropanoid Pathway by Resting Cells of Phomopsis sp. XP-8. PLOS ONE, 2015, 10:e0137066.
16. Li, H., Wang, Y. X., Li, L., Xu, Q. Q., Han, R. B., Wu, Z. Y., & Zhang, Y*. (2024). Debittering and antioxidant activity of fermented grapefruit juice with lactiplantibacillus plantarum 1-1-2.
17. 王晨曦,李乾弘,刘阳洲 & 张艳*.(2024).植物乳杆菌发酵对沙棘果汁中苦味物质的转化作用.食品工业科技,45(16),159-167.
18.滕迎弟,王晨曦,陈一凡,孔俊凯,王艺璇,兰正会... & 张艳*.(2024).双歧杆菌的有益代谢物生成途径及其健康作用和应用.食品科学,45(19),287-295.
19. 魏小晶, 周桓丞, 靳亚梅, 蔡静静, 倪永清*, 张艳*.新疆喀什地区维吾尔族婴幼儿肠道双歧杆菌遗传差异及益生特性分析, 食品科学, 2020.
20. 李小娟,倪永清*, 张艳*.新疆喀什地区维吾尔族群体不同哺乳期母乳中乳杆菌的种群多样性[J].食品科学, 2018.
21. 赵志霞, 许翠, 安美玲, 魏小晶, 廖宁, 倪永清*, 张艳*. 新疆喀什地区维吾尔族母乳源双歧杆菌分离筛选及其益生特性分析[J].食品科学, 2018.
专利
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一种菌株、菌剂及应用, 专利号：CN109679879B (授权).
一种保加利亚乳杆菌BSTS6-4及其应用, 专利号：CN110129220B (授权).
一种驴乳源戊糖片球菌及其应用, 专利号：CN112375696A.
一种母乳源戊糖片球菌及其应用, 专利号：CN111793586A.
一种暹罗芽孢杆菌及其应用, 专利号：CN111718881A.
承担教学
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主要承担本科生课程《食品微生物学》、《食品生物化学》、《食品安全学》及研究生课程《高级食品微生物学》等。
公司产品
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每年招收硕士研究生1-2名。
